Styles made his début in the 35th episode of the series, where he comfortably unseated one-time winner Steve Collins with a century. The next day, Styles amassed 120 points, with flawless numbers rounds and a spot of his first nine-letter word ROADSTERS. Despite flagging with 74 points out of a possible 162 in his fourth victory, Styles bounced back and climbed to a personal best of 128 points in his seventh game against previous Series 61 contestant Paul Varlaam. On his eighth appearance, Styles scored his fifth century and became the third octochamp of the series with a cumulative score of 820 points, six below Ian Volante's 826.
Following a 14-week hiatus due to the COVID-19 pandemic, number 5-ranked Styles returned in December 2020 to play his quarter-final match against number 4-ranked Volante. Although Styles managed to force a crucial conundrum by winning the very difficult final numbers round, he never took the lead throughout. He buzzed in on the last second of the match, but didn't answer and was ultimately ousted by the higher seed in his first defeat. His final series total is 896 points.
|#||Date||Type||Contestant 1||Score||Contestant 2||Guest||Lex||Max|
|7266||19/02/2020||P||Steve Collins||57 – 104||Ryan Styles||Janet Street-Porter||Susie Dent||124|
|7267||20/02/2020||P||Ryan Styles||120 – 57||Barbara Danks||Janet Street-Porter||Susie Dent||139|
|7268||21/02/2020||P||Ryan Styles||98 – 44||Charlie Delaney||Janet Street-Porter||Susie Dent||126|
|7269||24/02/2020||P||Ryan Styles||74 – 42||Julian Hawthorne||Dr Linda Papadopoulos||Susie Dent||162|
|7270||25/02/2020||P||Ryan Styles||100 – 36||Andy Hey||Dr Linda Papadopoulos||Susie Dent||144|
|7271||26/02/2020||P||Ryan Styles||96 – 77||John Robinson||Dr Linda Papadopoulos||Susie Dent||132|
|7272||27/02/2020||P||Ryan Styles||128 – 76||Paul Varlaam||Dr Linda Papadopoulos||Susie Dent||146|
|7273||28/02/2020||P||Ryan Styles||100 – 56||Trish Lodge||Dr Linda Papadopoulos||Susie Dent||124|
|7410||15/12/2020||QF||Ian Volante||82 – 76||Ryan Styles||John Inverdale||Susie Dent||119|